{"id":6552,"date":"2022-01-19T12:43:11","date_gmt":"2022-01-19T17:43:11","guid":{"rendered":"https:\/\/abudinen.com\/blog\/?p=6552"},"modified":"2022-01-21T21:09:22","modified_gmt":"2022-01-22T02:09:22","slug":"suplementos-nutricionales","status":"publish","type":"post","link":"https:\/\/abudinen.com\/blog\/2022\/01\/19\/suplementos-nutricionales\/","title":{"rendered":"Suplementos nutricionales"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Son los suplementos nutricionales siempre beneficiosos? Algunos eligen suplementarse porque siendo esclavos piensan que encontrar\u00e1n en ello los nutrientes que requieren. <em>La ciencia no es de unos pocos. Por falta de conocimiento las personas se pierden.<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Here\u2019s the difference between natural and synthetic nutrients:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Natural nutrients:<\/strong>&nbsp;These are obtained from whole food sources in the diet.<\/li><li><strong>Synthetic nutrients:<\/strong>&nbsp;Also referred to as isolated nutrients, these are usually made artificially, in an industrial process.<\/li><\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Synthetic nutrients do not include \u201cwhole food supplements,\u201d which are made from concentrated, dehydrated whole foods. https:\/\/www.healthline.com\/nutrition\/synthetic-vs-natural-nutrients#TOC_TITLE_HDR_2<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">When it comes to maintaining zinc levels, synthetic zinc supplements should be taken with caution. https:\/\/marinehealthfoods.com\/natural-zinc-supplement-vs-synthetic-zinc-supplement-which-should-i-choose\/#:~:text=When%20it%20comes%20to%20maintaining,should%20be%20taken%20with%20caution.&amp;text=It%20contains%20not%20only%20very,vitamin%20B12%20our%20bodies%20need.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For example, test-tube and animal studies have shown that&nbsp;<a href=\"https:\/\/www.healthline.com\/health\/ellagic-acid\" rel=\"noopener nofollow\">ellagic acid<\/a>&nbsp;can block tumor growth and cause tumor cell death in a variety of cancers (<a target=\"_blank\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4069806\/\" rel=\"noreferrer noopener nofollow\">21Trusted Source<\/a>).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Research progress on the anticarcinogenic actions and mechanisms of ellagic acid<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Hong-Mei Zhang, Lei Zhao, [&#8230;], and Lin Tao <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4069806\/#__ffn_sectitle\" rel=\"noopener nofollow\">Additional article information<\/a> <strong>Abstract<\/strong> Cancer is a leading cause of death worldwide. Cancer treatments by chemotherapeutic agents, surgery, and radiation have not been highly effective in reducing the incidence of cancers and increasing the survival rate of cancer patients. In recent years, plant-derived compounds have attracted considerable attention as alternative cancer remedies for enhancing cancer prevention and treatment because of their low toxicities, low costs, and low side effects. Ellagic acid (EA) is a natural phenolic constituent. Recent&nbsp;<em>in vitro<\/em>&nbsp;and&nbsp;<em>in vivo<\/em>&nbsp;experiments have revealed that EA elicits anticarcinogenic effects by inhibiting tumor cell proliferation, inducing apoptosis, breaking DNA binding to carcinogens, blocking virus infection, and disturbing inflammation, angiogenesis, and drug-resistance processes required for tumor growth and metastasis. This review enumerates the anticarcinogenic actions and mechanisms of EA. It also discusses future directions on the applications of EA.<strong>KEYWORDS :&nbsp;<\/strong>Ellagic acid (EA), cancer, mechanism https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4069806\/<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Kakadu plums contain roughly 228\u201314,020 mg of ellagic acid per 3.5 ounces (100 grams) of dried fruit. The exact amount is determined by the tree, climate, soil conditions, ripeness, and storage conditions (<a target=\"_blank\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28460910\" rel=\"noreferrer noopener nofollow\">19Trusted Source<\/a>). https:\/\/www.healthline.com\/nutrition\/kakadu-plum-benefits#57.-Other-benefits<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Organic acids in Kakadu plum (Terminalia ferdinandiana): The good (ellagic), the bad (oxalic) and the uncertain (ascorbic)<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">David J Williams&nbsp;et al.&nbsp;Food Res Int.&nbsp;2016 Nov. <strong>Abstract<\/strong> The phenolic ellagic acid (EA) is receiving increasing attention for its nutritional and pharmacological potential as an antioxidant and antimicrobial agent. The Australian native Kakadu plum (Terminalia ferdinandiana) fruit is an abundant source of this phytochemical. The fruit also contains large amounts of vitamin C (mainly as ascorbic acid, AA) and possibly the undesirable oxalic acid (OA). Regular consumption of high oxalate foods poses a variety of health risks in humans including interference with calcium absorption and kidney stone formation. Oxalate is also the end-product of AA metabolism so that consumption of fruit with heightened AA content has the potential to elevate urinary oxalate levels. The aims of this study were to investigate the distribution of EA and the presence of other bioactives in other Kakadu plum tissues. Chemical analysis of Kakadu plum fruit and leaves for EA (free and total), OA (water-soluble and total), calcium (Ca) and AA indicated that EA and AA concentrations were high in the fruit while the leaves had significantly higher EA levels but little or no detectable AA. OA content in fruit and leaves was substantial with the fruit being placed in the high-Oxalate category. These findings suggest that there is potential to elevate oxalate levels in the urine of susceptible people and intake of fruit-derived products should be closely monitored. By measuring tissues collected from specific trees, high EA-producing or low OA-containing individuals were identified. <strong>Keywords:&nbsp;<\/strong>Identification of individual trees possessing high bioactive tissues; Kakadu plum fruit and leaves; Link between oxalic and ascorbic acids; Nutraceutical plant; Oxalate: Calcium ratio; Quantification of organic acids. <i>Solo para usuarios registrados<\/i><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Leprosy, also called Hansen\u2019s disease, is a contagious disease. One way it spreads is from person to person. Even so, it\u2019s actually hard to catch. According to the Centers for Disease Control and Prevention (CDC), about 95% of humans are immune to the bacteria that cause this disease<sup>1<\/sup>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Because so many people are immune, how we catch it is still a bit of a mystery.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Scientists have learned that to catch leprosy, a healthy person must have months of close contact with someone who has leprosy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.aad.org\/public\/diseases\/a-z\/leprosy-risk\" rel=\"noopener nofollow\">https:\/\/www.aad.org\/public\/diseases\/a-z\/leprosy-risk<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>SciELO<\/strong>&nbsp;(<strong>Scientific Electronic Library Online<\/strong>&nbsp;o&nbsp;<strong>Biblioteca Cient\u00edfica Electr\u00f3nica en L\u00ednea<\/strong>) es un proyecto de&nbsp;<a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Biblioteca_electr%C3%B3nica\" rel=\"noopener nofollow\">biblioteca electr\u00f3nica<\/a>, iniciativa de la Fundaci\u00f3n para el Apoyo a la Investigaci\u00f3n del&nbsp;<a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Estado_de_S%C3%A3o_Paulo\" rel=\"noopener nofollow\">Estado de S\u00e3o Paulo<\/a>,&nbsp;<a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Brasil\" rel=\"noopener nofollow\">Brasil<\/a>&nbsp;(<em><a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Fundaci%C3%B3n_de_Apoyo_a_la_Investigaci%C3%B3n_del_Estado_de_S%C3%A3o_Paulo\" rel=\"noopener nofollow\">Fundaci\u00f3n de Apoyo a la Investigaci\u00f3n del Estado de S\u00e3o Paulo<\/a><\/em>&nbsp;\u2014 FAPESP) y del&nbsp;<a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Centro_Latinoamericano_y_del_Caribe_de_Informaci%C3%B3n_en_Ciencias_de_la_Salud\" rel=\"noopener nofollow\">Centro Latinoamericano y del Caribe de Informaci\u00f3n en Ciencias de la Salud<\/a>&nbsp;(BIREME),<sup><a href=\"https:\/\/es.m.wikipedia.org\/wiki\/SciELO#cite_note-1\" rel=\"noopener nofollow\">[1]<\/a><\/sup>\u200b que permite la publicaci\u00f3n electr\u00f3nica de ediciones completas de las&nbsp;<a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Revista_cient%C3%ADfica\" rel=\"noopener nofollow\">revistas cient\u00edficas<\/a>&nbsp;mediante una plataforma de&nbsp;<a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Software\" rel=\"noopener nofollow\">software<\/a>&nbsp;que posibilita el acceso a trav\u00e9s de distintos mecanismos, incluyendo&nbsp;<a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Enumeraci%C3%B3n\" rel=\"noopener nofollow\">listas<\/a>&nbsp;de t\u00edtulos y por materia,&nbsp;<a href=\"https:\/\/es.m.wikipedia.org\/wiki\/%C3%8Dndice\" rel=\"noopener nofollow\">\u00edndices<\/a>&nbsp;de autores y materias y un&nbsp;<a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Motor_de_b%C3%BAsqueda\" rel=\"noopener nofollow\">motor de b\u00fasqueda<\/a>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><sup>[1]<\/sup>&nbsp;Brito, Marcilio de (2001).&nbsp;<a href=\"http:\/\/revues.enssib.fr\/titre\/8etudca\/2scielo\/1modele.htm\" rel=\"noopener nofollow\">\u00abPr\u00e9sentation de la biblioth\u00e8que \u00e9lectronique SciELO et de ses DTD\u00bb<\/a>.&nbsp;<em>Guide pour les revues num\u00e9riques<\/em>. Consultado el 17 de enero de 2018.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Evidence Based Medicine: How we (should) make decisions in science and medicine<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">High-level versus Low-level Evidence &#8211; the Hierarchy of Medical Evidence https:\/\/www.meehanmd.com\/articles\/post\/173679\/an-evidence-based-scientific-analysis-of-why-masks-are-ineffective-unnecessary-and-harmful<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Advocates for mask mandates simply don\u2019t have the highest-levels of scientific evidence to support their arguments. They can only cite low-level science &#8211; retrospective observational studies.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Evidence hierarchies are often applied in evidence-based practices and are integral to decision making in medicine and the practice of evidence-based medicine (EBM). The following is from the <a href=\"https:\/\/en.wikipedia.org\/wiki\/Hierarchy_of_evidence\" rel=\"noopener nofollow\">Wikipedia definition and description of this issue<\/a>:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A hierarchy of evidence (or levels of evidence) is a heuristic used to rank the relative strength of results obtained from scientific research. There is broad agreement on the relative strength of large-scale, epidemiological studies.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">More than 80 different hierarchies have been proposed for assessing medical evidence.[1] The design of the study (such as a case report for an individual patient or a blinded randomized controlled trial) and the endpoints measured (such as survival or quality of life) affect the strength of the evidence. In clinical research, the best evidence for treatment efficacy is mainly from meta-analyses of randomized controlled trials (RCTs).[2][3] Typically, systematic reviews of completed, high-quality randomized controlled trials \u2013 such as those published by the <a href=\"https:\/\/en.wikipedia.org\/wiki\/Cochrane_(organisation)\" rel=\"noopener nofollow\">Cochrane Collaboration<\/a> \u2013 rank as the highest quality of evidence above observational studies, while expert opinion and anecdotal experience are at the bottom level of evidence quality.[2][4]<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>Siegfried T (2017-11-13).&nbsp;<a href=\"https:\/\/www.sciencenews.org\/blog\/context\/critique-medical-evidence-hierarchies\" rel=\"noopener nofollow\">&amp;amp;amp;quot;Philosophical critique exposes flaws in medical evidence hierarchies&amp;amp;amp;quot;<\/a>. Science News. Retrieved 2018-05-16.<\/li><li>Shafee, Thomas; Masukume, Gwinyai; Kipersztok, Lisa; Das, Diptanshu; H\u00e4ggstr\u00f6m, Mikael; Heilman, James (28 August 2017).&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5847101\" rel=\"noopener nofollow\">&amp;amp;amp;quot;Evolution of Wikipedia&amp;amp;amp;#x27;s medical content: past, present and future&amp;amp;amp;quot;;<\/a>. Journal of Epidemiology and Community Health. 71 (11): jech\u20132016\u2013208601.&nbsp;<a href=\"https:\/\/en.wikipedia.org\/wiki\/Doi_(identifier)\" rel=\"noopener nofollow\">doi<\/a>:<a href=\"https:\/\/doi.org\/10.1136%2Fjech-2016-208601\" rel=\"noopener nofollow\">10.1136\/jech-2016-208601<\/a>.&nbsp;<a href=\"https:\/\/en.wikipedia.org\/wiki\/ISSN_(identifier)\" rel=\"noopener nofollow\">ISSN<\/a>&nbsp;<a href=\"https:\/\/www.worldcat.org\/issn\/0143-005X\" rel=\"noopener nofollow\">0143-005X<\/a>.&nbsp;<a href=\"https:\/\/en.wikipedia.org\/wiki\/PMC_(identifier)\" rel=\"noopener nofollow\">PMC<\/a>&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5847101\" rel=\"noopener nofollow\">5847101<\/a>.&nbsp;<a href=\"https:\/\/en.wikipedia.org\/wiki\/PMID_(identifier)\" rel=\"noopener nofollow\">PMID<\/a>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28847845\" rel=\"noopener nofollow\">28847845<\/a>.<\/li><li>Straus SE, Richardson WS, Glasziou P, Haynes RB (2005). Evidence-based Medicine: How to Practice and Teach EBM (3rd ed.). Edinburgh: Churchill Livingstone. pp. 102\u201305.&nbsp;<a href=\"https:\/\/en.wikipedia.org\/wiki\/ISBN_(identifier)\" rel=\"noopener nofollow\">ISBN<\/a>&nbsp;<a href=\"https:\/\/en.wikipedia.org\/wiki\/Special:BookSources\/978-0443074448\" rel=\"noopener nofollow\">978-0443074448<\/a>.<\/li><li>Kim Hugel (16 May 2013).&nbsp;<a href=\"https:\/\/www.capho.org\/blog\/journey-research-levels-evidence\" rel=\"noopener nofollow\">&amp;amp;amp;quot;The Journey of Research &#8211; Levels of Evidence&amp;amp;amp;quot;<\/a>. Canadian Association of Pharmacy in Oncology. Retrieved 8 December 2019.<\/li><\/ol>\n\n\n\n<p class=\"wp-block-paragraph\">READ <strong>Matthew 15:11<\/strong> com\u00fan vs inmundo <strong>Levitico<\/strong> El aislamiento es para el enfermo, no para los sanos<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Agua de mar y salud bucodental, beneficios y recomendaciones<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><em>30 Julio, 2019 <a href=\"https:\/\/www.grupollona.es\/grupo-llona\/\" rel=\"noopener nofollow\">Grupo Llona<\/a>,&nbsp;<a href=\"https:\/\/www.grupollona.es\/salud-bucodental\/\" rel=\"noopener nofollow\">Salud Bucodental<\/a><a href=\"https:\/\/www.grupollona.es\/tag\/agua-con-cloro\/\" rel=\"noopener nofollow\">Agua Con Cloro<\/a>,&nbsp;<a href=\"https:\/\/www.grupollona.es\/tag\/agua-con-sal\/\" rel=\"noopener nofollow\">Agua Con Sal<\/a>,&nbsp;<a href=\"https:\/\/www.grupollona.es\/tag\/agua-de-mar\/\" rel=\"noopener nofollow\">Agua De Mar<\/a>,&nbsp;<a href=\"https:\/\/www.grupollona.es\/tag\/agua-de-mar-y-salud-bucodental\/\" rel=\"noopener nofollow\">Agua De Mar Y Salud Bucodental<\/a>,&nbsp;<a href=\"https:\/\/www.grupollona.es\/tag\/salud-bucodental\/\" rel=\"noopener nofollow\">Salud Bucodental<\/a><\/em> https:\/\/www.grupollona.es\/agua-de-mar-y-salud-bucodental-beneficios-y-recomendaciones\/#:~:text=Agua%20de%20mar%2C%20en%20enjuague,curaci%C3%B3n%20de%20extracciones%20y%20heridas.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Agua de mar, en enjuague o bebida, es muy&nbsp;beneficiosa&nbsp;en boca y contribuye a una buena salud bucodental y general. Interviene positivamente en procesos inflamatorios de las enc\u00edas, previene la caries y el mal aliento, desinfecta, calma el dolor y acelera la curaci\u00f3n de extracciones y heridas. Adem\u00e1s. se comporta eficazmente en el cuidado de la gingivitis y la periodontitis y, lo mejor, sin efectos secundarios, como alteraci\u00f3n del gusto o tinci\u00f3n dental.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Research has linked social isolation and loneliness to&nbsp;<strong>higher risks<\/strong>&nbsp;for a variety of physical and mental conditions: high blood pressure, heart disease, obesity, a weakened immune system, anxiety, depression, cognitive decline, Alzheimer&#8217;s disease, and even death.23 abr 2019<img decoding=\"async\" src=\"blob:https:\/\/abudinen.com\/cd85fa8c-a4b7-4e6c-9477-a0bfe0609e77\" alt=\"\">https:\/\/www.nia.nih.gov&nbsp;\u203a news \u203a so&#8230; <a href=\"https:\/\/www.nia.nih.gov\/news\/social-isolation-loneliness-older-people-pose-health-risks#:~:text=Research%20has%20linked%20social%20isolation,Alzheimer's%20disease%2C%20and%20even%20death.\">Social isolation, loneliness in older people pose health risks<\/a> <\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Leviticus 13:46<\/strong> https:\/\/www.studylight.org\/interlinear-study-bible\/greek\/leviticus\/13-45.html \u1f00\u03ba\u03ac\u03b8\u03b1\u03c1\u03c4\u03bf\u03c2<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Diet-Related Risk Factors for Leprosy: A Case-Control Study<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Inge Wagenaar, Lisanne van Muiden, [&#8230;], and Jan Hendrik Richardus <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4428634\/#__ffn_sectitle\" rel=\"noopener nofollow\">Additional article information<\/a> Associated Data <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4428634\/#\" rel=\"noopener nofollow\">Supplementary MaterialsData Availability Statement<\/a> Abstract Background Food shortage was associated with leprosy in two recent studies investigating the relation between socioeconomic factors and leprosy. Inadequate intake of nutrients due to food shortage may affect the immune system and influence the progression of infection to clinical leprosy. We aimed to identify possible differences in dietary intake between recently diagnosed leprosy patients and control subjects. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4428634\/\" rel=\"noopener nofollow\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4428634\/<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u00c1CIDO ASC\u00d3RBICO vs Vitamin C <strong>Whole Vs. Fractionated<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In addition to avoiding isolate supplements, it\u2019s also a good idea to steer clear of vitamins that aren\u2019t made by nature. Unfortunately, the most common form of vitamin C found in supplements&nbsp; is ascorbic acid, which is a laboratory-made synthetic\u2014often sourced from genetically modified corn. Although ascorbic acid chemically similar to vitamin C, it\u2019s not truly identical. It\u2019s missing some of the vital elements that make natural vitamin C so beneficial\u2014such as rutin, bioflavonoids, factor K, factor J, factor P, and ascorbinogen. Ascorbic acid may also reduce copper levels and upset the balance of your delicate microbiome. To compound these issues, synthetic sources of vitamin C may be highly acidic, which could make it more difficult for your body to absorb nutrients from the healthy foods you eat.&nbsp;https:\/\/sarifoods.co\/blogs\/news\/129938951-the-benefits-of-natural-vitamin-c<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">REVIEW https:\/\/www.saludestrategica.com\/acido-ascorbico-vs-vitamina-c\/<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Este \u00e1cido tiene propiedades antioxidantes (por eso se usa con frecuencia como conservante alimentario) que &nbsp;ayudan a evitar la degradaci\u00f3n del resto de elementos de la vitamina C. Adem\u00e1s, el \u00e1cido asc\u00f3rbico tiene propiedades antis\u00e9pticas y por eso suele ir bien (a corto plazo) para apoyar al sistema inmune en su lucha contra pat\u00f3genos.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter\"><img decoding=\"async\" src=\"https:\/\/sp-ao.shortpixel.ai\/client\/q_glossy,ret_img,w_539\/https:\/\/www.saludestrategica.com\/wp-content\/uploads\/2016\/12\/vitamina-c-vs-acido-ascorbico.jpg\" alt=\"vitamina c vs acido ascorbico\" class=\"wp-image-6456\"\/><\/figure><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Los elementos del complejo vitamina C son los siguientes:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>\u00c1cido asc\u00f3rbico<\/li><li>Bioflavonoides<\/li><li>Factor P (o \u201cvitamina\u201d P): un compuesto hidrosoluble tambi\u00e9n conocido como rutina que promueve la resistencia capilar (\u00bftienes varices?). Es un&nbsp;flavonoide que se encuentra en algunos alimentos vegetales como los esp\u00e1rragos y los c\u00edtricos<\/li><li>Factor K (o vitamina K)<\/li><li>Factor J (o \u201cvitamina\u201d J). A veces la&nbsp;<strong>colina<\/strong>&nbsp;recibe este nombre, e incluso se le llega a agrupar junto con las vitaminas del grupo B.<\/li><li><a target=\"_blank\" href=\"https:\/\/es.wikipedia.org\/wiki\/Tirosinasa\" rel=\"noreferrer noopener nofollow\"><strong>Tirosinasa<\/strong><\/a> es una enzima presente en los tejidos de plantas y animales que contiene cobre como cofactor y se encarga de catalizar la producci\u00f3n de melanina (el pigmento del pelo y la piel) a partir del amino\u00e1cido tirosina mediante oxidaci\u00f3n.<\/li><\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">A la vista de esta informaci\u00f3n, comprar \u00e1cido asc\u00f3rbico pensando que es vitamina C es como ir al concesionario a comprar un coche e irte de all\u00ed con un chasis nuevo y reluciente pero sin ruedas, motor ni volante. Para que el \u00e1cido asc\u00f3rbico sea realmente vitamina C debe combinarse con los dem\u00e1s componentes.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Known Tyrosinase inhibitors are the following:<sup><a href=\"https:\/\/en.m.wikipedia.org\/wiki\/Tyrosinase#cite_note-22\" rel=\"noopener nofollow\">[22]<\/a><\/sup><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><a href=\"https:\/\/en.m.wikipedia.org\/wiki\/Azelaic_acid\" rel=\"noopener nofollow\">Azelaic acid<\/a><\/li><li><a href=\"https:\/\/en.m.wikipedia.org\/wiki\/Hydroquinone\" rel=\"noopener nofollow\">Hydroquinone<\/a><\/li><li><a href=\"https:\/\/en.m.wikipedia.org\/wiki\/Arbutin\" rel=\"noopener nofollow\">Arbutin<\/a><\/li><li><a href=\"https:\/\/en.m.wikipedia.org\/wiki\/Kojic_acid\" rel=\"noopener nofollow\">Kojic acid<\/a><\/li><li><a href=\"https:\/\/en.m.wikipedia.org\/wiki\/Vitamin_C\" rel=\"noopener nofollow\"><em>L<\/em>-ascorbic acid<\/a>&nbsp;&#8211; Vitamin C<\/li><li><a href=\"https:\/\/en.m.wikipedia.org\/wiki\/Ellagic_acid\" rel=\"noopener nofollow\">Ellagic acid<\/a><\/li><li><a href=\"https:\/\/en.m.wikipedia.org\/wiki\/Tranexamic_acid\" rel=\"noopener nofollow\">Tranexamic acid<\/a><\/li><\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><sup>[22]<\/sup>&nbsp;Pillaiyar T, Manickam M, Namasivayam V (December 2017).&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6010116\" rel=\"noopener nofollow\">&#8220;Skin whitening agents: medicinal chemistry perspective of tyrosinase inhibitors&#8221;<\/a>.&nbsp;<em>Journal of Enzyme Inhibition and Medicinal Chemistry<\/em>.&nbsp;<strong>32<\/strong>&nbsp;(1): 403\u2013425.&nbsp;<a href=\"https:\/\/en.m.wikipedia.org\/wiki\/Doi_(identifier)\" rel=\"noopener nofollow\">doi<\/a>:<a href=\"https:\/\/doi.org\/10.1080%2F14756366.2016.1256882\" rel=\"noopener nofollow\">10.1080\/14756366.2016.1256882<\/a>.&nbsp;<a href=\"https:\/\/en.m.wikipedia.org\/wiki\/PMC_(identifier)\" rel=\"noopener nofollow\">PMC<\/a><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6010116\" rel=\"noopener nofollow\">6010116<\/a>.&nbsp;<a href=\"https:\/\/en.m.wikipedia.org\/wiki\/PMID_(identifier)\" rel=\"noopener nofollow\">PMID<\/a><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28097901\" rel=\"noopener nofollow\">28097901<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Influence of Vitamin P (Vitamin C<sub>2<\/sub>) upon the Amount of Ascorbic Acid in the Organs of the Guinea Pig<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.nature.com\/articles\/161557a0#auth-H_-COTEREAU\" rel=\"noopener nofollow\">H. COTEREAU<\/a>,&nbsp;<a href=\"https:\/\/www.nature.com\/articles\/161557a0#auth-M_-GABE\" rel=\"noopener nofollow\">M. GABE<\/a>,&nbsp;\u2026 <a href=\"https:\/\/www.nature.com\/articles\/161557a0#auth-J__L_-PARROT\" rel=\"noopener nofollow\">J.-L. PARROT<\/a>&nbsp;<a href=\"https:\/\/www.nature.com\/\" rel=\"noopener nofollow\"><em>Nature<\/em><\/a>&nbsp;<strong>volume&nbsp;161<\/strong>,&nbsp;pages557\u2013558 (1948) <a href=\"https:\/\/www.nature.com\/articles\/161557a0#citeas\" rel=\"noopener nofollow\">Cite this article<\/a> 79&nbsp;Accesses 27&nbsp;Citations 3&nbsp;Altmetric <a href=\"https:\/\/www.nature.com\/articles\/161557a0\/metrics\" rel=\"noopener nofollow\">Metricsdetails<\/a> <strong>Abstract<\/strong> WE have put forward previously the view that vitamin P acts upon vitamin C as a \u2018sparing factor&#8217; by slowing down its oxidation; this factor should be indispensable, for without it the organism would need vitamin C in much larger quantities than can be supplied by a normal diet<sup>1<\/sup>. This theory led us to carry out two series of experiments. The first showed that various substances capable of raising the mean capillary resistance of a group of guinea pigs decrease&nbsp;<em>in vitro<\/em>&nbsp;oxidation of&nbsp;<em>l<\/em>-ascorbic acid<sup>2<\/sup>. The other showed that&nbsp;<em>l<\/em>-ascorbic acid, administered to guinea pigs, even in large doses and over a long period, is inefficient if the animals are given at the same time a diet deficient in an ascorbic acid economizing factor. Conversely, if vitamin P is added,&nbsp;<em>l<\/em>-ascorbic acid, even in small doses, becomes fully efficient ; vitamin P alone, without ascorbic acid, has no effect. The tests used were the mean capillary resistance of a group of guinea pigs and the histological picture of the thyroid gland and of the cortico-adrenal gland<sup>3<\/sup>. https:\/\/www.nature.com\/articles\/161557a0<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">REVIEW Whole Food Vitamins: Ascorbic Acid Is Not Vitamin C \u2013 by Timothy O\u2019Shea, medical researcher https:\/\/www.justlivewell.com\/whole-food-vitamins-ascorbic-acid-is-not-vitamin-c\/ Without further ado, here\u2019s the kernel: ascorbic acid is not vitamin C. Alpha tocopherol is not vitamin E. Retinoic acid is not vitamin A. And so on through the other vitamins. Vast sums of money have been expended to make these myths part of Conventional Wisdom. If you have several college degrees and all this is news to you, don\u2019t feel bad. Unless you think your education ended at Commencement. Which is generally true.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Going off on a tangent, ever wondered how the FDA attained its present position as attack dog for the drug companies and food manufacturers? It\u2019s another whole story in itself. The precursor of the FDA was the Bureau of Chemistry. Up until 1912 the Bureau of Chemistry was headed up by a man named Dr. Harvey W. Wiley. Here\u2019s a quote from Dr. Wiley that illustrates where his interests lay:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cNo food product in our country would have any trace of benzoic acid, sulfurous acid or sulfites or any alum or saccharin, save for medical purposes. No soft drink would contain caffeine or theobromine. No bleached flour would enter interstate commerce. Our foods and drugs would be wholly without any form of adulteration and misbranding. The health of our people would be vastly improved and the life greatly extended. The manufacturers of our food supply, and especially the millers, would devote their energies to improving the public health and promoting happiness in every home by the production of whole ground, unbolted cereal flours and meals.\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>\u2013 The History of a Crime Against the Pure Food Law,1912<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Now obviously we can\u2019t have a dangerous lunatic like this in charge of the public nutrition, can we? Dr. Wiley actually filed suit against the Coca-Cola company in an attempt to keep their artificial product out of interstate commerce, and off the market. Fortunately, Wiley was eventually replaced by a saner individual, more attuned to the real nutritional needs of the American people, as determined by the experts who knew what was best for us: the food manufacturers. This was Dr. Elmer Nelson, and in his words we get an idea of the change in philosophy that marked the transformation of the Bureau of Chemistry into the FDA: \u201cIt is wholly unscientific to state that a well-fed body is more able to resist disease than a poorly-fed body. My overall opinion is that there hasn\u2019t been enough experimentation to prove that dietary deficiencies make one susceptible to disease.\u201d \u2013 Elmer Nelson MD, Washington Post 26 Oct 49<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In addition,&nbsp;mineral co-factors must be available in proper amounts.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If any of these parts are missing, there is no vitamin C, no vitamin activity. When some of them are present, the body will draw on its own stores to make up the differences, so that the whole vitamin may be present. Only then will vitamin activity take place, provided that all other conditions and co-factors are present. Ascorbic acid is described merely as the \u201cantioxidant wrapper\u201d portion of vitamin C; ascorbic acid protects the functional parts of the vitamin from rapid oxidation or breakdown. (Somer, p 58 \u201cVitamin C: A Lesson in Keeping An Open Mind\u201d The Nutrition Report)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">I remember Dr. E. M. Nelson, &#8211; Elmer Nelson was head of the Division of Nutrition at that time, &#8211; he told the Commissioner that this development of inter-Division teams on specific pro-jects was one of the best things that had happened. <a href=\"https:\/\/www.google.com\/url?sa=t&amp;source=web&amp;rct=j&amp;url=https:\/\/www.fda.gov\/media\/81602\/download&amp;ved=2ahUKEwiTuqiZ_L31AhV5STABHaZSCvoQFnoECAsQAQ&amp;usg=AOvVaw22kgkkxKbGguUoAAW7_Iak\" rel=\"noopener nofollow\">https:\/\/www.fda.gov&nbsp;\u203a&nbsp;mediaPDFFDA Oral History Interview, Roe<\/a>M. Nelson, &#8211; Elmer Nelson was head of the Division of. Nutrition at that time, &#8211; he told the Commissioner that this<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Eat like yourancestors: Not your grandmother, but your great-g-g-g-g-g-g-g-grandmother!<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Did you know that in 1906 when flour bleaching became more widespread that the FDA banned it from use? A mere six years later the FDA changed its stance because Dr. Nelson, new director of the FDA in 1912, unbelievingly said, \u201c<em>It is wholly unscientific to state that a well-fed body is more able to resist disease than a poorly fed body. My overall opinion is that there hasn\u2019t been enough experimentation to prove that dietary deficiencies make one susceptible to disease.<\/em>\u201d Well, we sure know that\u2019s not true! And in regard to white flour, many studies since have confirmed that the bleaching process results in byproducts that are toxic to humans. In fact, many processed foods have been the target of research that shows there are hidden dangers in these foods that can impact human health. Scary things abound, such as the fast-food hamburger that didn\u2019t decay after being kept on a shelf for 12 years and another famous fast-food chain\u2019s \u201ctaco beef filling\u201d that is only 36% meat. Food just isn\u2019t food anymore. https:\/\/www.waldenu.edu\/news-and-events\/spotlight\/2013\/guest-blog-we-interrupt-this-diet-for-important-message<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">REVIEW Dr. Elmer M. Nelson took his place in 1912 and is quoted in the Washington Post, October 26, 1949 https:\/\/www.thrivinghealthny.com\/post\/2018\/04\/02\/gleaning-from-the-food-of-yesterday-the-fda-1<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">January 13, 2014 http:\/\/www.arthurhaines.com\/blog\/2014\/6\/13\/vitamin-c-and-ascorbic-acid-are-not-the-same-thing<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">We have been trained in this country to think of many things as isolated features.&nbsp;&nbsp;Whether it is nutrition, or medicine, or even how we examine ourselves relative to the environment we live in, we are convinced that we can understand complex structures and processes by understanding the individual parts.&nbsp;&nbsp;This belief has led to a tremendous amount of confusion, failure of medicine, and poor nutritional practices.&nbsp;&nbsp;A classic example of this confusion is osteoporosis, a progressive decrease in bone density that creates a risk of fractures.&nbsp;&nbsp;This condition was long treated with calcium supplementation.&nbsp;&nbsp;However, simply supplementing with this mineral can lead to calcium being deposited in the wrong place (i.e., not in the bones), such as in the joints (leading to osteoarthritis) and in the blood vessels (leading to atherosclerosis).&nbsp;&nbsp;Calcium has several co-factors it needs to work properly in the body, such as vitamin D, vitamin K2, and magnesium, along with saturated fat (to assist with the incorporation of calcium in the bones) and exercise (to stress the bones). Without these co-factors, some of the calcium ends up in the wrong place.&nbsp;&nbsp;This example clearly points to the logical fallacy of thinking that a given health issue can be repaired by supplementing with a single nutritional factor.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Though European explorers and colonists have a long history of succumbing to vitamin C deficiency (scurvy), this vitamin is ever present on the landscape and easy to incorporate in the diet. Relying on synthetic vitamin C does not provide the full spectrum of health benefits found in naturally occurring vitamin C and misses the point that vitamins don\u2019t act alone but rather in concert with minerals, macronutrients, various compounds, and other vitamins.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Why getting vitamin C through ascorbic acid is a problem<\/strong> https:\/\/www.northcoast.organic\/beware-ascorbic-acid-synthetic-vitamin-c\/#:~:text=According%20to%20an%20article%20in,should%20have%20reason%20to%20worry.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">According to an article in&nbsp;<a target=\"_blank\" href=\"http:\/\/www.thehealthyhomeeconomist.com\/beware-of-ascorbic-acid-synthetic\/\" rel=\"noreferrer noopener nofollow\">The Healthy Home Economist<\/a>, ascorbic acid is actually synthetic vitamin C, usually derived from GMO corn. And, there is a growing body of evidence that those consuming high doses of ascorbic acid should have reason to worry.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The Winter 2009 edition of&nbsp;<a target=\"_blank\" href=\"http:\/\/westonaprice.org\/\" rel=\"noreferrer noopener nofollow\"><em>Wise Traditions<\/em><\/a>&nbsp;cites 3 studies, which give pause about large doses of vitamin C. The first study (from the Jun 15, 2001 issue of&nbsp;<em>Science<\/em>) showed that \u201csynthetic vitamin C may contribute to the formation of genotoxins that can lead to cancer.\u201d A second study presented to the American Heart Association showed a link between consumption of only 500mg of vitamin C per day and a greater propensity toward thickening of the arteries (<em>Los Angeles Times<\/em>, March 3, 2000).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Even more recently, athletes taking 1000mg of vitamin C per day showed reduced endurance capacity from interference with antioxidant enzymes (<em>American Journal of Clinical Nutrition<\/em>, Jan 2008).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Instead of getting extra vitamin C through ascorbic acid, the article recommends&nbsp;<strong>non ascorbic acid vitamin C supplements<\/strong>. There are many types available on the market.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"headline\">Vitamin C Produces Gene-Damaging Compounds, Test-Tube Study In&nbsp;<em>Science<\/em>&nbsp;Reports<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Date:June 15, 2001Source:American Association For The Advancement Of ScienceSummary:Vitamin C, known to be a DNA-protecting &#8220;antioxidant,&#8221; is a switch hitter, also capable of inducing the production of DNA-damaging compounds, suggests a study in the 15 June issue of the international journal, Science. Mutations caused by these compounds have been found in a variety of tumors. https:\/\/www.sciencedaily.com\/releases\/2001\/06\/010615072358.htm<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">REVIEW https:\/\/chroniclingamerica.loc.gov\/<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.science.org\/toc\/science\/292\/5524\" rel=\"noopener nofollow\">BACK TO VOL. 292, NO. 5524<\/a> Vitamin C-Induced Decomposition of Lipid Hydroperoxides to Endogenous Genotoxins <a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.1059501#con1\" rel=\"noopener nofollow\">SEON HWA&nbsp;LEE<\/a><a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.1059501#con2\" rel=\"noopener nofollow\">TOMOYUKI&nbsp;OE<\/a>AND&nbsp;<a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.1059501#con3\" rel=\"noopener nofollow\">IAN A.&nbsp;BLAIR<\/a>&nbsp;fewer&nbsp;<a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.1059501#tab-contributors\" rel=\"noopener nofollow\">Authors Info &amp; Affiliations<\/a><strong><em>SCIENCE<\/em><\/strong>&nbsp;\u2022&nbsp;15 Jun 2001&nbsp;\u2022&nbsp;Vol&nbsp;292,&nbsp;Issue&nbsp;5524&nbsp;\u2022&nbsp;pp.&nbsp;2083-2086&nbsp;\u2022&nbsp;<a href=\"https:\/\/doi.org\/10.1126\/science.1059501\" rel=\"noopener nofollow\">DOI: 10.1126\/science.1059501<\/a> Epidemiological data suggest that dietary antioxidants play a protective role against cancer. This has led to the proposal that dietary supplementation with antioxidants such as vitamin C (vit C) may be useful in disease prevention. However, vit C has proved to be ineffective in cancer chemoprevention studies. In addition, concerns have been raised over potentially deleterious transition metal ion\u2013mediated pro-oxidant effects. We have now determined that vit C induces lipid hydroperoxide decomposition to the DNA-reactive bifunctional electrophiles 4-oxo-2-nonenal, 4,5-epoxy-2(<em>E<\/em>)-decenal, and 4-hydroxy-2-nonenal. The compound 4,5-Epoxy-2(<em>E<\/em>)-decenal is a precursor of etheno-2\u2032-deoxyadenosine, a highly mutagenic lesion found in human DNA. Vitamin C\u2013mediated formation of genotoxins from lipid hydroperoxides in the absence of transition metal ions could help explain its lack of efficacy as a cancer chemoprevention agent. https:\/\/www.science.org\/doi\/10.1126\/science.1059501<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Can Vitamin C Damage DNA?<\/strong> Supplement appears to spur formation of toxins <strong>14 JUN 2001<\/strong> BY <a href=\"https:\/\/www.science.org\/content\/author\/martha-downs\" rel=\"noopener nofollow\">MARTHA DOWNS<\/a> <a href=\"https:\/\/www.science.org\/content\/article\/can-vitamin-c-damage-dna\" rel=\"noopener nofollow\">https:\/\/www.science.org\/content\/article\/can-vitamin-c-damage-dna<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Large Doses of Vitamin C Supplements Linked to Atherosclerosis BY&nbsp;<a href=\"https:\/\/news.usc.edu\/author\/alicia-di-rado\/\" rel=\"noopener nofollow\">Alicia Di Rado<\/a>MARCH 27, 2000 Regular intake of vitamin C pills over time may quicken the thickening of artery walls, a condition known as atherosclerosis, according to USC Keck School of Medicine researchers. https:\/\/news.usc.edu\/7559\/Large-Doses-of-Vitamin-C-Supplements-Linked-to-Atherosclerosis\/#:~:text=Regular%20intake%20of%20vitamin%20C,Keck%20School%20of%20Medicine%20researchers. People taking about 500 mg of vitamin C in supplements each day for a year showed a progression in carotid wall thickness that was 2.5 times greater than those who did not take a vitamin C supplement, whether they were men or women. And the higher the dose, Dwyer said, the greater the atherosclerosis progression.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance&nbsp;<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"javascript:;\">Mari-Carmen Gomez-Cabrera<\/a>,&nbsp;<a href=\"javascript:;\">Elena Domenech<\/a>,&nbsp;<a href=\"javascript:;\">Marco Romagnoli<\/a>,&nbsp;<a href=\"javascript:;\">Alessandro Arduini<\/a>,&nbsp;<a href=\"javascript:;\">Consuelo Borras<\/a>,&nbsp;<a href=\"javascript:;\">Federico V Pallardo<\/a>,&nbsp;<a href=\"javascript:;\">Juan Sastre<\/a>,&nbsp;<a href=\"javascript:;\">Jose Vi\u00f1a<\/a><em>The American Journal of Clinical Nutrition<\/em>, Volume 87, Issue 1, January 2008, Pages 142\u2013149,&nbsp;<a href=\"https:\/\/doi.org\/10.1093\/ajcn\/87.1.142\" rel=\"noopener nofollow\">https:\/\/doi.org\/10.1093\/ajcn\/87.1.142<\/a>Published:&nbsp;01 January 2008 https:\/\/academic.oup.com\/ajcn\/article\/87\/1\/142\/4633311<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Background:<\/strong>&nbsp;Exercise practitioners often take vitamin C supplements because intense muscular contractile activity can result in oxidative stress, as indicated by altered muscle and blood glutathione concentrations and increases in protein, DNA, and lipid peroxidation. There is, however, considerable debate regarding the beneficial health effects of vitamin C supplementation.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Objective:<\/strong>&nbsp;This study was designed to study the effect of vitamin C on training efficiency in rats and in humans.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Design:<\/strong>&nbsp;The human study was double-blind and randomized. Fourteen men (27\u201336 y old) were trained for 8 wk. Five of the men were supplemented daily with an oral dose of 1 g vitamin C. In the animal study, 24 male Wistar rats were exercised under 2 different protocols for 3 and 6 wk. Twelve of the rats were treated with a daily dose of vitamin C (0.24 mg\/cm<sup>2<\/sup>&nbsp;body surface area).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Results:<\/strong>&nbsp;The administration of vitamin C significantly (<em>P<\/em>&nbsp;= 0.014) hampered endurance capacity. The adverse effects of vitamin C may result from its capacity to reduce the exercise-induced expression of key transcription factors involved in mitochondrial biogenesis. These factors are peroxisome proliferator\u2013activated receptor co-activator 1, nuclear respiratory factor 1, and mitochondrial transcription factor A. Vitamin C also prevented the exercise-induced expression of cytochrome C (a marker of mitochondrial content) and of the antioxidant enzymes superoxide dismutase and glutathione peroxidase.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Conclusion:<\/strong>&nbsp;Vitamin C supplementation decreases training efficiency because it prevents some cellular adaptations to exercise.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Son los suplementos nutricionales siempre beneficiosos? Algunos eligen suplementarse porque siendo esclavos piensan que encontrar\u00e1n en ello los nutrientes que requieren. La ciencia no es de unos pocos. 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