{"id":6847,"date":"2022-01-31T18:25:23","date_gmt":"2022-01-31T23:25:23","guid":{"rendered":"https:\/\/abudinen.com\/blog\/?p=6847"},"modified":"2022-01-31T18:25:24","modified_gmt":"2022-01-31T23:25:24","slug":"virus-and-poison","status":"publish","type":"post","link":"https:\/\/abudinen.com\/blog\/2022\/01\/31\/virus-and-poison\/","title":{"rendered":"Virus and poison"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\" id=\"the-good-that-viruses-do\"><strong>The Good That Viruses Do<\/strong> Annual Review of Virology Vol. 4:iii-v (Volume publication date September 2017)<br><a href=\"https:\/\/doi.org\/10.1146\/annurev-vi-04-071217-100011\" rel=\"noopener nofollow\">https:\/\/doi.org\/10.1146\/annurev-vi-04-071217-100011<\/a> In fact, some viruses have beneficial properties for their hosts in a symbiotic relationship (<a href=\"https:\/\/www.annualreviews.org\/doi\/10.1146\/annurev-vi-04-071217-100011#\" rel=\"noopener nofollow\">1<\/a>), while other natural and laboratory-modified viruses can be used to target and kill cancer cells, to treat a variety of genetic diseases as gene and cell therapy tools, or to serve as vaccines or vaccine delivery agents. The ability to treat diseases using viruses, often referred to as virotherapy, has become the subject of intensive research in recent years. https:\/\/www.annualreviews.org\/doi\/10.1146\/annurev-vi-04-071217-100011<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Roossinck MJ<\/strong>.&nbsp;<strong>2011<\/strong>.&nbsp;The good viruses: viral mutualistic symbioses.&nbsp;<em>Nat. Rev. Microbiol.<\/em>&nbsp;9:99\u2013108 <a href=\"https:\/\/www.annualreviews.org\/servlet\/linkout?suffix=B1&amp;dbid=16&amp;doi=10.1146%2Fannurev-vi-04-071217-100011&amp;key=10.1038%2Fnrmicro2491\" rel=\"noopener nofollow\">Crossref<\/a> <a href=\"https:\/\/www.annualreviews.org\/servlet\/linkout?suffix=B1&amp;dbid=8&amp;doi=10.1146%2Fannurev-vi-04-071217-100011&amp;key=21200397\" rel=\"noopener nofollow\">Medline<\/a> <a href=\"https:\/\/www.annualreviews.org\/servlet\/linkout?suffix=B1&amp;dbid=128&amp;doi=10.1146%2Fannurev-vi-04-071217-100011&amp;key=000286176600011\" rel=\"noopener nofollow\"><em>Web of Science<\/em>&nbsp;\u00ae<\/a> <a href=\"http:\/\/scholar.google.com\/scholar_lookup?hl=en&amp;publication_year=2011&amp;author=MJ+Roossinck&amp;title=The+good+viruses%3A+viral+mutualistic+symbioses\" rel=\"noopener nofollow\">Google Scholar<\/a> <a href=\"https:\/\/www.annualreviews.org\/doi\/10.1146\/annurev-vi-04-071217-100011#\" rel=\"noopener nofollow\">Article Location<\/a> More AR articles citing this reference<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">NIH: &#8220;Characteristics of Antiviral Agents That Are Approved or Under Evaluation for the Treatment of COVID-19&#8221;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">RE: Ivermectin &lt;Some have reported that there has been a &#8220;silent&#8221; update made to this key NIH website. I cannot personally verify this.&gt;<br>&#8230;<br>NIH: &#8220;The dose most commonly used in clinical trials is IVM 0.2\u20130.6 mg\/kg PO given as a single dose or as a once-daily dose for up to 5 days.&#8221; Roger that?<br>&#8230;<br>Most serious side effects- &#8220;Neurological AEs have been reported when IVM has been used to treat parasitic diseases, but it is not clear whether these AEs were caused by IVM or the underlying conditions.&#8221;<br><a target=\"_blank\" href=\"https:\/\/www.covid19treatmentguidelines.nih.gov\/tables\/table-2e\/\" rel=\"noreferrer noopener nofollow\">https:\/\/www.covid19treatmentguidelines.nih.gov\/tables\/table-2e\/<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">READ https:\/\/www.dsalud.com\/revistas\/numero-170-abril-2014\/cartas-al-director https:\/\/www.dsalud.com\/revistas\/numero-116-mayo-2009\/cartas-al-director <\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"marvel-star-evangeline-lilly-protests-covid-19-vaccine-mandates-i-am-still-pro-choice\"><strong>Marvel star Evangeline Lilly protests COVID-19 vaccine mandates: &#8216;I am still pro choice&#8217;<\/strong> CHARLES TREPANY&nbsp;|&nbsp;USA TODAY&nbsp;|&nbsp;17 hours ago https:\/\/www.usatoday.com\/story\/entertainment\/celebrities\/2022\/01\/27\/marvel-evangeline-lilly-protests-covid-vaccine-mandate\/9249232002\/<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Evangeline Lilly is speaking out against COVID-19 vaccine mandates on social media.<\/li><li>\u200b\u200b\u200b\u200b\u200b\u200b\u200bThe &#8220;Ant-Man and the Wasp&#8221; star shared she attended a protest &#8220;to support bodily sovereignty&#8221; over the weekend.<\/li><li>&#8220;This is not the way,&#8221; the Marvel star wrote. &#8220;This is not love.&#8221;<\/li><li>In March 2020, Lilly sparked controversy when she downplayed COVID-19 as both a &#8220;respiratory flu&#8221;&nbsp;and a possible political ploy.<\/li><\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Trimetoprim-sulfametoxazol (Bactrim) y nitrofuranto\u00edna (Macrobid).<strong>&nbsp;Ciertos medicamentos para las infecciones urinarias pueden aumentar el riesgo de defectos de nacimiento, advierten los funcionarios<\/strong><br><em>(Certain UTI medications may raise risk of birth defects, officials warn)<\/em><br><em>CBS News,<\/em>&nbsp;13 de enero de 2018<br><a href=\"http:\/\/5newsonline.com\/2018\/01\/13\/certain-uti-medications-may-raise-risk-of-birth-defects-officials-warn\/\" rel=\"noopener nofollow\">http:\/\/5newsonline.com\/2018\/01\/13\/certain-uti-medications-may-raise-risk-of-birth-defects-officials-warn\/<\/a><br>Traducido por Salud y F\u00e1rmacos https:\/\/www.saludyfarmacos.org\/lang\/es\/boletin-farmacos\/boletines\/ago201801\/09_tri\/<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/biblearchaeologyreport.com\/\" rel=\"noopener nofollow\">https:\/\/biblearchaeologyreport.com\/<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"helicobacter-pylori-a-beneficial-gastric-pathogen\"><em>Helicobacter pylori<\/em>: A Beneficial Gastric Pathogen?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Amin Talebi Bezmin Abadi <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#__ffn_sectitle\" rel=\"noopener nofollow\">Additional article information<\/a> <strong>Introduction<\/strong> Since&nbsp;<em>Helicobacter pylori<\/em>&nbsp;(<em>H. pylori<\/em>) is the first successful culture three decades ago, ongoing perspectives regarding the relationship between the bacterium and human health have changed radically (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B1\" rel=\"noopener nofollow\">1<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B2\" rel=\"noopener nofollow\">2<\/a>). Apart from tremendous studies performed during the last years, there are still many debates regarding the unclear rationale for existence of such bacteria in human stomach (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B3\" rel=\"noopener nofollow\">3<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B4\" rel=\"noopener nofollow\">4<\/a>). Basically, due to the beneficiary effects of&nbsp;<em>H. pylori<\/em>&nbsp;colonization (regression in child asthma and other allergic disorders), it has been concluded that&nbsp;<em>H. pylori<\/em>&nbsp;is a common flora or at least harmless bacterium (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B5\" rel=\"noopener nofollow\">5<\/a>\u2013<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B10\" rel=\"noopener nofollow\">10<\/a>), Conversely, because of the causative role of&nbsp;<em>H. pylori<\/em>&nbsp;in certain digestive diseases such as duodenal ulcer and gastric cancer, other reports are quite contradictory (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B11\" rel=\"noopener nofollow\">11<\/a>\u2013<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B13\" rel=\"noopener nofollow\">13<\/a>). A large number of discussions led to a consensus regarding presence of&nbsp;<em>H. pylori<\/em>&nbsp;in the human stomach (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B5\" rel=\"noopener nofollow\">5<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B11\" rel=\"noopener nofollow\">11<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B14\" rel=\"noopener nofollow\">14<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B15\" rel=\"noopener nofollow\">15<\/a>). Our knowledge about biology of&nbsp;<em>H. pylori<\/em>&nbsp;suggests that the bacterium is highly adapted to stay in gastric mucosa for long time (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B1\" rel=\"noopener nofollow\">1<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B16\" rel=\"noopener nofollow\">16<\/a>). Indeed, living in lower surface of gastric mucosa, with no bacterial competition, provided a novel place to survive. Moreover,&nbsp;<em>H. pylori<\/em>&nbsp;is able to multiply freely due to the protective effects by mucosal layer. Thus,&nbsp;<em>H. pylori<\/em>&nbsp;had an opportunity to thrive in stomach over the course of tens of thousands of years of co-evolution with humans (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B17\" rel=\"noopener nofollow\">17<\/a>). Additionally, the high frequency of mutation in the genome also led to higher chances of survival, and natural selection helped them to remain and cause chronic infection (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B18\" rel=\"noopener nofollow\">18<\/a>). Determining whether&nbsp;<em>H. pylori<\/em>&nbsp;is beneficial or detrimental in human stomach has been a challenging area of research in gastroenterology (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B5\" rel=\"noopener nofollow\">5<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B11\" rel=\"noopener nofollow\">11<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B19\" rel=\"noopener nofollow\">19<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B20\" rel=\"noopener nofollow\">20<\/a>). In this article, we aim to elucidate various aspects of this persistent colonization of this beneficial infection.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"S1-2title\"><strong>GERD and&nbsp;<em>H. pylori<\/em>: A good example of beneficial effects<\/strong> Gastroesophageal reflux disease (GERD) incidence has been increased mostly in developed communities where&nbsp;<em>H. pylori<\/em>&nbsp;infection is almost effectively eradicated (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B27\" rel=\"noopener nofollow\">27<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B28\" rel=\"noopener nofollow\">28<\/a>). GERD is the main risk factor for Barrett\u2019s esophagus, and it has been associated with another deadly gastroduodenal carcinoma called \u201cesophageal adenocarcinoma\u201d (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B3\" rel=\"noopener nofollow\">3<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B5\" rel=\"noopener nofollow\">5<\/a>). However, the relationship between GERD and&nbsp;<em>H. pylori<\/em>&nbsp;remains incompletely defined (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B29\" rel=\"noopener nofollow\">29<\/a>). Several studies suggested that eradication of&nbsp;<em>H. pylori<\/em>&nbsp;infection in the setting of duodenal ulcer disease would result in an increase in GERD symptoms (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B3\" rel=\"noopener nofollow\">3<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B30\" rel=\"noopener nofollow\">30<\/a>). In other words, an inverse association of&nbsp;<em>H. pylori<\/em>&nbsp;infection with decreased rate of this sort of disease was a challenging topic in new gastroenterology (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B14\" rel=\"noopener nofollow\">14<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B31\" rel=\"noopener nofollow\">31<\/a>\u2013<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B33\" rel=\"noopener nofollow\">33<\/a>). Of note, GERD and its sequelae, which include Barrett\u2019s esophagus and esophageal adenocarcinoma, is decreasing in countries in which most individuals are infected by&nbsp;<em>H. pylori<\/em>&nbsp;(<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B15\" rel=\"noopener nofollow\">15<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B34\" rel=\"noopener nofollow\">34<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B35\" rel=\"noopener nofollow\">35<\/a>). Actually, not only has worldwide&nbsp;<em>H. pylori<\/em>&nbsp;prevalence changed in recent decades but also other environmental factors affecting on human health such as socioeconomical levels, diet, and vaccination were drastically changed (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B10\" rel=\"noopener nofollow\">10<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B17\" rel=\"noopener nofollow\">17<\/a>). If so,&nbsp;<em>H. pylori<\/em>&nbsp;is confronting with different situation rather than before. Remarkably,&nbsp;<em>H. pylori<\/em>&nbsp;can undergo drastic genetic change through each generation, while human genes do not change frequently. As a result, frequent genetic changes in&nbsp;<em>H. pylori<\/em>&nbsp;helped the bacterium to adapt quickly (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B18\" rel=\"noopener nofollow\">18<\/a>). Remarkably, slower adaptation in humans deteriorates longtime established equilibrium between&nbsp;<em>H. pylori<\/em>&nbsp;and human. Because of this, elimination of&nbsp;<em>H. pylori<\/em>&nbsp;as permanent resident of human microbiome would not be the first option to deal with gastroduodenal diseases. According to what explained about GERD and&nbsp;<em>H. pylori<\/em>&nbsp;as a protective effect, the long cohabitation in our stomach calls for more deep studies to elucidate microbiota and human health. GERD is the best example of disease, which became more frequent after starting the&nbsp;<em>H. pylori<\/em>&nbsp;treatment (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B34\" rel=\"noopener nofollow\">34<\/a>). Indeed, after antibiotic usage against&nbsp;<em>H. pylori<\/em>&nbsp;and, of course, its eradication in Western countries, a constant equilibrium between&nbsp;<em>H. pylori<\/em>&nbsp;and human health disappeared. Interestingly, in Northeastern Malaysia, the low prevalence of&nbsp;<em>H. pylori<\/em>&nbsp;infection was frequently reported (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B36\" rel=\"noopener nofollow\">36<\/a>\u2013<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B38\" rel=\"noopener nofollow\">38<\/a>). As general rule, one expects that frequency of diseases such as asthma and GERD should be relatively low rather than the findings of expected inverse association were not found (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B39\" rel=\"noopener nofollow\">39<\/a>\u2013<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B41\" rel=\"noopener nofollow\">41<\/a>). Actually, the association between&nbsp;<em>H. pylori<\/em>&nbsp;infection and certain diseases such as GERD and asthma risk can be affected by geographical and genetic differences (<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B37\" rel=\"noopener nofollow\">37<\/a>,&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/#B41\" rel=\"noopener nofollow\">41<\/a>). As a result, there is a complex and mostly undetermined associations between human microbiome and health; accordingly, all attempts to change this arranged biological system can exacerbate certain diseases. Undoubtedly, we need to eradicate virulent&nbsp;<em>H. pylori<\/em>&nbsp;in people with adverse clinical manifestations, but this conclusion cannot be generalized to all&nbsp;<em>H. pylori<\/em>&nbsp;positive subjects. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4291894\/<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The mortality rate related to H pylori infection is not precisely known, but it seems to be minimal (ie, <strong>approximately 2%-4% of all infected people<\/strong>). Mortality is due to the complications of the infection, such as gastric ulcer perforation or MALTomas of the GI tract.<img decoding=\"async\" src=\"blob:https:\/\/abudinen.com\/d586ab5a-86bf-43cf-9fe7-46f2ebd6903b\" alt=\"\">https:\/\/www.medscape.com&nbsp;\u203a answers <a href=\"https:\/\/www.medscape.com\/answers\/176938-44717\/what-is-the-mortality-rate-for-helicobacter-pylori-h-pylori-infection\" rel=\"noopener nofollow\">What is the mortality rate for Helicobacter pylori (H &#8230; &#8211; Medscape<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For most people the infection <strong>won&#8217;t cause them any problems<\/strong>. But in some, H. pylori can cause long-lasting irritation, swelling and pain in the stomach (known as &#8216;severe chronic atrophic gastritis&#8217; or SCAG) and stomach ulcers. This can lead to cancer.6 sept 2021<img decoding=\"async\" src=\"blob:https:\/\/abudinen.com\/82cc4958-6f28-4b56-9f8c-054cdf918565\" alt=\"\">https:\/\/www.cancerresearchuk.org&nbsp;\u203a &#8230; <a href=\"https:\/\/www.cancerresearchuk.org\/about-cancer\/causes-of-cancer\/infections-eg-hpv-and-cancer\/does-hpylori-cause-cancer\" rel=\"noopener nofollow\">Does H.pylori cause cancer?<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Se denomina&nbsp;<strong>c\u00e1mara Kirlian<\/strong>&nbsp;a una&nbsp;<a href=\"https:\/\/es.m.wikipedia.org\/wiki\/C%C3%A1mara_fotogr%C3%A1fica\" rel=\"noopener nofollow\">c\u00e1mara<\/a>&nbsp;capaz de plasmar en una imagen el&nbsp;<a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Efecto_corona\" rel=\"noopener nofollow\">efecto corona<\/a>&nbsp;de cualquier objeto u organismo al aplicar un&nbsp;<a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Campo_el%C3%A9ctrico\" rel=\"noopener nofollow\">campo el\u00e9ctrico<\/a>&nbsp;sobre una placa. La fotograf\u00eda Kirlian est\u00e1 directamente relacionada con el fen\u00f3meno el\u00e9ctrico de los&nbsp;<a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Fuegos_de_san_Telmo\" rel=\"noopener nofollow\">fuegos de san Telmo<\/a>. Se ha demostrado que la fotograf\u00eda Kirlian solo indica variaciones de presi\u00f3n, humedad, contacto a tierra y conductividad. La&nbsp;<a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Efecto_corona\" rel=\"noopener nofollow\">descarga de corona<\/a>&nbsp;es un fen\u00f3meno bien conocido que se explica en f\u00edsica elemental.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Research note: Although copper does have anti-inflammatory properties and has shown benefit for reducing heart disease and Alzheimer&#8217;s disease, <strong>there currently is no research to support dietary copper or supplements as a treatment for arthritis<\/strong>.<img decoding=\"async\" src=\"blob:https:\/\/abudinen.com\/b96e6e64-7155-43bf-99a4-ed4b4776e6e8\" alt=\"\">https:\/\/www.arthritis.org&nbsp;\u203a treatment <a href=\"https:\/\/www.arthritis.org\/health-wellness\/treatment\/complementary-therapies\/supplements-and-vitamins\/vitamin-and-mineral-guide-for-arthritis\" rel=\"noopener nofollow\">Vitamin and Mineral Guide for Arthritis<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Some people spread pathogens less than others perhaps because of their immune system<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"1\u00b0entrevista al Dr. Stefan Lanka por Mark Pfister - \u00bfCu\u00e1les Virus? - COMPLETO en ESPA\u00d1OL\" width=\"1200\" height=\"675\" src=\"https:\/\/www.youtube.com\/embed\/v9Gd2s7e3QQ?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">1\u00b0entrevista al Dr. Stefan Lanka por Mark Pfister &#8211; \u00bfCu\u00e1les Virus? &#8211; COMPLETO en ESPA\u00d1OL 201810 oct El Dr Stefan Lanka, micro-bi\u00f3logo, nos habla de la realidad de las investigaciones cient\u00edficas inherentes a la presunta existencia de los virus. \u00bfCient\u00edfico? \u00bfQu\u00e9 quiere decir? \u00bfCu\u00e1les son las bases de los conocimientos cient\u00edficos disponibles en medicina? \u00bfEn qu\u00e9 se basan? \u00bfCiencia o negocios? Este video fue presentado al Congreso Open Day de nuestra Escuela de Formaci\u00f3n Profesional sobre las 5LB con el tema: &#8220;los fundamentos. la validez y los l\u00edmites de los conocimientos m\u00e9dicos-cient\u00edficos&#8221;. www.5lbtraining.com<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"page-title\">Risk of myocarditis following sequential COVID-19 vaccinations by age and sex<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Martina&nbsp;Patone,&nbsp;Xue W&nbsp;Mei,&nbsp;Lahiru&nbsp;Handunnetthi,&nbsp;Sharon&nbsp;Dixon,&nbsp;Francesco&nbsp;Zaccardi,&nbsp;Manu&nbsp;Shankar-Hari,&nbsp;Peter&nbsp;Watkinson,&nbsp;Kamlesh&nbsp;Khunti,&nbsp;Anthony&nbsp;Harnden,&nbsp;Carol AC&nbsp;Coupland,&nbsp;Keith M.&nbsp;Channon,&nbsp;<a target=\"_blank\" href=\"http:\/\/orcid.org\/0000-0003-0533-7991\" rel=\"noreferrer noopener nofollow\">&nbsp;View ORCID Profile<\/a>Nicholas L&nbsp;Mills,&nbsp;Aziz&nbsp;Sheikh,&nbsp;Julia&nbsp;Hippisley-Cox<strong>doi:<\/strong>&nbsp;https:\/\/doi.org\/10.1101\/2021.12.23.21268276<a target=\"_blank\" href=\"https:\/\/www.medrxiv.org\/content\/what-unrefereed-preprint\" rel=\"noreferrer noopener nofollow\">This article is a preprint and has not been peer-reviewed [what does this mean?]. It reports new medical research that has yet to be evaluated and so should&nbsp;<em>not<\/em>&nbsp;be used to guide clinical practice.<\/a> In an updated self-controlled case series analysis of 42,200,614 people aged 13 years or more, we evaluate the association between COVID-19 vaccination and myocarditis, stratified by age and sex, including 10,978,507 people receiving a third vaccine dose. Myocarditis risk was increased during 1-28 days following a third dose of BNT162b2 (IRR 2.02, 95%CI 1.40, 2.91). Associations were strongest in males younger than 40 years for all vaccine types with an additional 3 (95%CI 1, 5) and 12 (95% CI 1,17) events per million estimated in the 1-28 days following a first dose of BNT162b2 and mRNA-1273, respectively; 14 (95%CI 8, 17), 12 (95%CI 1, 7) and 101 (95%CI 95, 104) additional events following a second dose of ChAdOx1, BNT162b2 and mRNA-1273, respectively; and 13 (95%CI 7, 15) additional events following a third dose of BNT162b2, compared with 7 (95%CI 2, 11) additional events following COVID-19 infection. An association between COVID-19 infection and myocarditis was observed in all ages for both sexes but was substantially higher in those older than 40 years. These findings have important implications for public health and vaccination policy. <strong>Funding<\/strong>&nbsp;Health Data Research UK. https:\/\/www.medrxiv.org\/content\/10.1101\/2021.12.23.21268276v1<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Generalmente, las principales agencias sanitarias del mundo reconocen a las diluciones de per\u00f3xido de hidr\u00f3geno de hasta 6&nbsp;% como seguras para su uso como agente antimicrobiano, agente oxidante<sup><a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Per%C3%B3xido_de_hidr%C3%B3geno#cite_note-10\" rel=\"noopener nofollow\">[10]<\/a><\/sup>\u200b<sup><a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Per%C3%B3xido_de_hidr%C3%B3geno#cite_note-11\" rel=\"noopener nofollow\">[11]<\/a><\/sup>\u200b y otros prop\u00f3sitos. Debido a su efecto oxidante, desde hace muchos a\u00f1os se ha utilizado como agente antis\u00e9ptico y antibacteriano. Su uso ha descendido los \u00faltimos a\u00f1os debido a la popularidad de otros productos sustitutivos. Todav\u00eda se utiliza en muchos hospitales, centros m\u00e9dicos y cl\u00ednicas.<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>D. Gonz\u00e1lez, I. Bejarano, C. Barriga, A.B. Rodr\u00edguez, J.A. Pariente (2010). &#8220;<a href=\"http:\/\/www.eurekaselect.com\/85761\/article\/oxidative-stress-induced-caspases-are-regulated-human-myeloid-hl-60-cells-calcium\/\" rel=\"noopener nofollow\">Oxidative Stress-Induced Caspases are Regulated in Human Myeloid HL-60 Cells by Calcium Signal<\/a>&#8220;. Current Signal Transduction Therapy&nbsp;<strong>5<\/strong>: 181-186.&nbsp;<a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Digital_object_identifier\" rel=\"noopener nofollow\">doi<\/a>:[10.2174\/157436210791112172]<\/li><li><a href=\"https:\/\/es.m.wikipedia.org\/wiki\/Per%C3%B3xido_de_hidr%C3%B3geno#cite_ref-11\" rel=\"noopener nofollow\">\u2191<\/a>&nbsp;Bejarano I, Espino J, Gonz\u00e1lez-Flores D, Casado JG, Redondo PC, Rosado JA, Barriga C, Pariente JA, Rodr\u00edguez AB (2009). &#8220;<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3614781\/\" rel=\"noopener nofollow\">Role of Calcium Signals on Hydrogen Peroxide-Induced Apoptosis in Human Myeloid HL-60 Cells<\/a>&#8220;. International Journal of Biomedical science&nbsp;<strong>5(3)<\/strong>: 246-256.<\/li><\/ol>\n\n\n\n<p class=\"wp-block-paragraph\">REVIEW La cura en un minuto. El secreto para curar pr\u00e1cticamente todas las enfermedades. Madison cavanaugh<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>New study focuses on growing enzymes on International Space Station to help develop nerve agent antidotes<\/strong> https:\/\/homelandprepnews.com\/stories\/23315-new-study-focuses-growing-enzymes-international-space-station-help-develop-nerve-agent-antidotes\/?amp<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The International Space Station\u2019s (ISS) microgravity environment could provide a means of improving the understanding of toxic nerve agents, such as sarin and VX, and how to combat them, according to a researchers from the National Institutes of Health (NIH)-supported Countermeasures Against Chemical Threats (CounterACT) project.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The project centers on the study of organophosphates (OPs), a family chemicals that work to block the enzyme acetylcholinesterase (AChE). AChE is important for the body\u2019s ability to allow muscles to relax after nervous system stimulation. When this enzyme is blocked by OPs such as sarin or VX, muscles cannot relax and the resulting condition leads to paralysis and potential death.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">According to NIH, developing antidotes to OP poisoning requires detailed knowledge about the structure of AChE, however, the forces of Earth\u2019s gravity have posed challenges to that area of research. This fact led researchers to send human AChE samples to ISS in June in order to grow large crystals of pure enzyme to a size not achievable on earth due to gravitational interference.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cBy taking advantage of the microgravity conditions of the International Space Station, we hope to grow better, more uniform crystals that we are unable to grow on Earth,\u201d Andrey Kovalevsky of the Oak Ridge National Laboratory said.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Once the enzyme crystals grow to a large enough size, the samples will be flown back down to earth to be analyzed via a method called neutron diffraction, which will provide an atomic-level view of the enzymes.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">University of California-San Diego (UCSD) researcher Zoran Radi\u0107 said the technique would enable researchers to get a closer look at how the enzyme interacts with pesticides and nerve agents and learn about how the bond between the two can be chemically reversed.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Contemporary countermeasures to OP exposure work by reactivating AChE by breaking its chemical bond with OP, however, the speed in which they become effective is too slow.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">NIH said in a release that the project will help researchers develop antidotes that break the AChE-OP bond more quickly and can be delivered orally, which is key when dealing with large-scale exposure to nerve poisons.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Contributions to the project have been made by the National Institute of Neurological Disorders and Stroke (NINDS), the Oak Ridge National Laboratory, UCSD, the University of Utah, and the NIH Office of the Director. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">PUBLISHED BYHPN News Desk5 YEARS AGO<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Masaje, moxibustion<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"9-venenos-que-curan\"><strong>9 venenos que curan<\/strong> La biomedicina busca en las sustancias t\u00f3xicas fabricadas por animales el remedio contra decenas de enfermedades. Usadas en peque\u00f1as dosis, pueden combatir el c\u00e1ncer, el dolor, el alzh\u00e9imer&#8230; https:\/\/www.muyinteresante.es\/naturaleza\/fotos\/9-venenos-que-curan<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"content\"><strong>La extraordinaria historia del hombre que se inyecta veneno letal de serpiente pero no se muere<\/strong> Redacci\u00f3n BBC Mundo 20 marzo 2017 https:\/\/www.bbc.com\/mundo\/noticias-39331284<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#8220;Mi sangre es \u00fanica porque llevo casi 30 a\u00f1os haciendo esto&#8221;, dice el entusiasta de las serpientes.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">La exposici\u00f3n gradual de Steve al veneno de serpiente ha funcionado de la misma manera que las vacunas funcionan para la mayor\u00eda de nosotros, explica la doctora Weston.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"content\"><strong>Por qu\u00e9 el veneno es una de las sustancias m\u00e1s \u00fatiles de la naturaleza<\/strong> Jonathan Amos Corresponsal de Ciencia de BBC 31 octubre 2017 &#8220;Sin veneno estar\u00edamos acabados&#8221;, dice el experto del Museo de Historia Natural de Londres, Ronald Jenner https:\/\/www.bbc.com\/mundo\/noticias-41819393<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#8220;Si comes&nbsp;<strong>frutas<\/strong>, estas est\u00e1n polinizadas por abejas, que son venenosas&#8221;, dice Ronald Jenner, experto en evoluci\u00f3n del veneno del NHM.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#8220;Los higos est\u00e1n polinizados por avispas parasitoides. Si comes&nbsp;<strong>calamares o pulpos,<\/strong>&nbsp;son venenosos&#8221;.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#8220;Los venenos se usan en cosm\u00e9ticos: las m\u00e1scaras para la cara usan una versi\u00f3n sint\u00e9tica del p\u00e9ptido de v\u00edbora que relaja los m\u00fasculos&#8221;, a\u00f1ade el cient\u00edfico.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#8220;Y puede que no lo sepas, pero tu&nbsp;<strong>remedio para la diabetes&nbsp;<\/strong>es probablemente un versi\u00f3n sint\u00e9tica de una toxina&#8221;.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">El veneno del murci\u00e9lago vampiro hace que la sangre de la presa contin\u00fae fluyendo.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Tambi\u00e9n<strong>&nbsp;el vino tiene veneno.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#8220;El vino tinto que bebes fue aclarado con las vejigas natatorias de un bagre venenoso. No lo ponen en la etiqueta, pero los tent\u00e1culos del veneno est\u00e1n por todas partes en tu vida diaria&#8221;, dice Jenner.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&#8220;La&nbsp;<strong>ropa de algod\u00f3n&nbsp;<\/strong>que usas&#8230; La \u00fanica raz\u00f3n por la que podemos cultivar algod\u00f3n en grandes monocultivos es porque las avispas parasitoides eliminan a los insectos que chupan la savia que, de otro modo, da\u00f1ar\u00edan las cosechas.&nbsp;<strong>Sin veneno, estar\u00edamos acabados<\/strong>&#8220;.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Algunos venenos espesan la sangre para producir co\u00e1gulos en la v\u00edctima, lo que a su vez provoca un derrame y una muerte r\u00e1pida.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Algunos venenos act\u00faan como agentes anticoagulantes. Los murci\u00e9lagos vampiro usan esta estrategia para poder seguir chupando sangre de una herida.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">El ejemplo m\u00e1s famoso es probablemente el del&nbsp;<em>Bothrops jararaca<\/em>, una serpiente brasile\u00f1a que puede r\u00e1pidamente hacer que le baje la presi\u00f3n a su v\u00edctima para que se desmaye y caiga al suelo.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Este veneno les mostr\u00f3 a los cient\u00edficos el camino para crear uno de las primeros tratamientos para la presi\u00f3n alta en seres humanos.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Despu\u00e9s est\u00e1 tambi\u00e9n el &#8220;monstruo de Gila&#8221;. La picadura dolorosa de este lagarto incorpora un p\u00e9ptido que regula la glucosa.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">AstraZeneca comercializa una droga basada en esta mol\u00e9cula llamada Exenatide que se utiliza para controlar la diabetes tipo 2. Su costo es de cientos de millones al a\u00f1o.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"who-healthy-people-still-don-t-need-to-wear-masks-for-coronavirus-protection-but-that-guidance-could-change\"><strong>WHO: Healthy people still don&#8217;t need to wear masks for coronavirus protection, but that guidance could change<\/strong> <a href=\"https:\/\/www.businessinsider.com\/author\/anna-medaris-miller\" rel=\"noopener nofollow\">Anna Medaris Miller<\/a>\u00a0Apr 1, 2020, 1:59 PM https:\/\/www.businessinsider.com\/who-healthy-people-dont-need-medical-masks-that-could-change-2020-4<a target=\"_blank\" href=\"https:\/\/www.facebook.com\/sharer\/sharer.php?u=https%3A%2F%2Fwww.businessinsider.com%2Fwho-healthy-people-dont-need-medical-masks-that-could-change-2020-4&amp;utmSource=facebook&amp;utmContent=referral&amp;utmTerm=topbar&amp;referrer=facebook\" rel=\"noreferrer noopener nofollow\"><\/a><a href=\"mailto:?subject=WHO:%20Healthy%20people%20still%20don%27t%20need%20to%20wear%20masks%20for%20coronavirus%20protection,%20but%20that%20guidance%20could%20change&amp;body=WHO%3A%20Healthy%20people%20still%20don%27t%20need%20to%20wear%20masks%20for%20coronavirus%20protection%2C%20but%20that%20guidance%20could%20change%0D%0A%0D%0Ahttps%3A%2F%2Fwww.businessinsider.com%2Fwho-healthy-people-dont-need-medical-masks-that-could-change-2020-4&amp;\"><\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">While he acknowledged there&#8217;s debate about whether\u00a0<a href=\"https:\/\/www.businessinsider.com\/how-to-make-an-effective-face-mask-at-home-2020-3\" rel=\"noopener nofollow\">healthy members of the community should wear masks<\/a>, Tedros said the WHO recommends medical masks &#8220;for people who are sick and those caring for them,&#8221; along with other protective measures.\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Good That Viruses Do Annual Review of Virology Vol. 4:iii-v (Volume publication date September 2017)https:\/\/doi.org\/10.1146\/annurev-vi-04-071217-100011 In fact, some viruses have beneficial properties for their hosts in a symbiotic relationship (1), while &#8230; <a title=\"Virus and poison\" class=\"read-more\" href=\"https:\/\/abudinen.com\/blog\/2022\/01\/31\/virus-and-poison\/\" aria-label=\"Read more about Virus and poison\">Leer m\u00e1s<\/a><\/p>\n<p class=\"social-share asbm-share-block\"><strong class=\"asbm-share-title\">Sharing is caring<\/strong><a href=\"https:\/\/www.facebook.com\/sharer.php?u=https%3A%2F%2Fabudinen.com%2Fblog%2F2022%2F01%2F31%2Fvirus-and-poison%2F\" target=\"_blank\" rel=\"noopener\" class=\"asbm-share asbm-share--facebook\" aria-label=\"Compartir en Facebook\"><svg viewBox=\"0 0 24 24\" width=\"18\" height=\"18\" fill=\"currentColor\" aria-hidden=\"true\"><path d=\"M9.101 23.691v-7.98H6.627v-3.667h2.474v-1.58c0-4.085 1.848-5.978 5.858-5.978.401 0 .955.042 1.468.103a8.68 8.68 0 0 1 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